|
|
|
|
|
|
|
|
|
|
Examples of the interactive forces between specific molecules
Petri P. Lehenkari, Guillaume T. Charras, Stephen A. Nesbitt and Mike A. Horton
|
Table 2. Examples of the interactive forces between specific molecules (tab002mhu) |
||
| Ligand–receptor or cell-structure interactions | Force (pN) | Refs |
| Proteins | ||
|
Meromyosin and actin |
15–25 | 7 |
| Avidin and biotin | 160–200 | 32, 34, 38, 58 |
| Streptavidin and biotin | 200–257 | 32, 79 |
| Cell-adhesion proteoglycans | 40–125 | 36 |
| Antibiotin antibody and biotin | 60 | 35 |
|
Anti-HAS and HAS; other antibodies and antigen |
49–244 | 30, 80 |
| P-selectin and glycoprotein ligand-1 | 165 | 38 |
| Cells | ||
| RGD and cell receptor | 35–120 | 42 |
| Trophoblast and uterine epithelium | 1000–16 000 | 28 |
| Cell and uncoated surface | 19 000–100 000 | 51 |
| Cell and coated surface | 100 000–220 000 | 51 |
|
Abbreviations used: HAS = human serum albumin; RGD = arginine–glycine–asparagine peptide motif |
||
|
References cited in Table 2 7 Nakajima, H. et al. (1997) Scanning force microscopy of the interaction events between a single molecule of heavy meromyosin and actin. Biochem Biophys Res Commun 234, 178-182, PubMed 28 Thie, M. et al. (1998) Interactions between trophoblast and uterine epithelium: monitoring of adhesive forces. Hum Reprod 13, 3211-3219, PubMed 30 Hinterdorfer, P. et al. (1996) Detection and localization of individual antibody-antigen recognition events by atomic force microscopy. Proc Natl Acad Sci U S A 93, 3477-3481, PubMed 32 Moy, V.T., Florin, E.L. and Gaub, H.E. (1994) Intermolecular forces and energies between ligands and receptors. Science 266, 257-259, PubMed 34 Florin, E.L., Moy, V.T. and Gaub, H.E. (1994) Adhesion forces between individual ligand-receptor pairs. Science 264, 415-417, PubMed 35 Dammer, U. et al. (1996) Specific antigen/antibody interactions measured by force microscopy. Biophys J 70, 2437-2441, PubMed 36 Dammer, U. et al. (1995) Binding strength between cell adhesion proteoglycans measured by atomic force microscopy. Science 267, 1173-1175, PubMed 38 Fritz, J. et al. (1998) Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy. Proc Natl Acad Sci U S A 95, 12283-12288, PubMed 42 Lehenkari, P.P. and Horton, M.A. (1999) Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy. Biochem Biophys Res Commun 259, 645-650, PubMed 51 Sagvolden, G. et al. (1999) Cell adhesion force microscopy. Proc Natl Acad Sci U S A 96, 471-476, PubMed 58 Merkel, R. et al. (1999) Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy. Nature 397, 50-53, PubMed 79 Wong, S.S. et al. (1998) Covalently functionalized nanotubes as nanometre-sized probes in chemistry and biology. Nature 394, 52-55, PubMed 80 Allen, S. et al. (1997) Detection of antigen-antibody binding events with the atomic force microscope. Biochemistry 36, 7457-7463, PubMed |