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Accession information: Vol. 7; Issue 11; 14 June 2005 Abstract
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Nesprin binding partners
Derek T. Warren, Qiuping Zhang, Peter L. Weissberg and Catherine M. Shanahan
| Table 3. Nesprin binding partners | |||
| Nesprin | Partner | Localisation | Refs |
| Nesprin-1 | Lamin A/C | Nuclear lamina | 13, 15 |
| Emerin | INM | 15 | |
| F-actin | Cytoskeleton | 23 | |
| MuSK | Neuromuscular junction | 16 | |
| KIF3B | MT-associated | 62 | |
| mAKAP | NE | 64 | |
| Nesprin-2 | Lamin A/C | Nuclear lamina | 14 |
| Emerin | INM | 14 | |
| F-actin | Cytoskeleton | 17 | |
| Ryanodine receptor | Sarcoplasmic reticulum, NE | 14 | |
| Abbreviations: INM, inner nuclear membrane; KIF3B, a kinesin subunit; mAKAP, muscle A-kinase anchor protein; MT, microtubule; MuSK, muscle-specific tyrosine kinase; NE, nuclear envelope. | |||
| References cited
in Table 3
13 Mislow, J.M. et al. (2002) Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett 525, 135-140, PubMed 14 Zhang, Q. et al. (2005) Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J Cell Sci 118, 673-687, PubMed 15 Mislow, J.M. et al. (2002) Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C. J Cell Sci 115, 61-70, PubMed 16 Apel, E.D. et al. (2000) Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem 275, 31986-31995, PubMed 17 Zhen, Y.Y. et al. (2002) NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. J Cell Sci 115, 3207-3222, PubMed 23 Padmakumar, V.C. et al. (2004) Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp Cell Res 295, 330-339, PubMed 62 Fan, J. and Beck, K.A. (2004) A role for the spectrin superfamily member Syne-1 and kinesin II in cytokinesis. J Cell Sci 117, 619-629, PubMed 64 Pare, G.C. et al. (2005) Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope. Exp Cell Res 303, 388-399, PubMed |
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