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Accession information: Vol. 7; Issue 15; 10 August 2005 Abstract
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The varicella–zoster virus glycoproteins

Mark Quinlivan and Judith Breuer

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Table 1. The varicella–zoster virus glycoproteins
Molecular mass (kDa)	Old name	HSV homologue	Essential for growth in cell culture?	Functions	Refs
60–98	gI	gE	Yes	Complexes with gI to form Fc receptor for nonimmune IgG, virus cell–cell spread, activates fusion function of gB	20, 52, 56, 58, 59, 60, 70, 174, 175
140	gII	gB	ND	Virus–host-cell attachment, entry, egress and virus cell–cell spread	53, 70, 176, 177
118	gIII	gH	Yes	Virus–host-cell entry, egress and virus cell–cell spread	20, 22, 176
60	gIV	gI	No	Complexes with gE to form Fc receptor for nonimmune IgG, virus cell–cell spread, viral envelopment, processing and cellular distribution of gE	23, 43, 48, 60, 178
95–105	gV	gC	No	Virus–host-cell attachmenta, skin infectivity	28, 107, 179, 180
18–20	gVI	gL	ND	Chaperone protein facilitating maturation, folding and transport of gH to the cell surface	49, 54, 181, 182
40	NA	gK	Yes	Virus–host-cell fusiona	183, 184
45	NA	gM	ND	Unknown	14, 185, 186
a Predicted function based on HSV-1. Abbreviations: HSV, herpes simplex virus; IgG, immunoglobulin G; NA not applicable; ND, not done.

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