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Expert Reviews in Molecular Medicine: http://www.expertreviews.org/
Accession information: Vol. 7; Issue 19; 20 September 2005 Abstract
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Comparison of cell-surface and molecular markers for human and mouse embryonic stem cells

Louise A. Hyslop, Lyle Armstrong, Miodrag Stojkovic and Majlinda Lako

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Table 2. Comparison of cell-surface and molecular markers for human and mouse embryonic stem cells
Marker hESCs mESCs Refs
SSEA-1 + 32, 33
SSEA-3 + 1, 2, 98, 109
SSEA-4 + 1, 2, 98, 109
TRA-1-60 + 1, 2, 98, 109
TRA-1-81 + 1, 2, 98, 109
TRA-254 + 109
GTCM-2 + 2, 110
Alkaline phosphatase + 98, 111
TG343 + ? 98, 110
Oct4 + + 1, 2, 38, 39, 40, 98
Nanog + + 44, 45, 98
Rex1 + + 98, 112
Foxd3 + +a 17, 98, 113
Tert + + 98, 114
Sox2 + + 98, 115
Fgfr4 + + 17
Utf1 + + 17
Terf1 + + 17
Terf2 + + 17
Cx45 + + 17
Cx43 + + 17
Glut1 + + 17
Bcrp1 + + 116
a Variable between cell lines.
Abbreviations: Bcrp1, breast cancer resistance protein 1; Cx43/45, connexin 43/45; Fgfr4, fibroblast growth factor receptor 4; Glut1, glucose transporter 1; Foxd3, forkhead box D3; Rex1, zinc finger protein 42; Sox2, SRY-related HMG-box gene 2; SSEA, stage-specific embryonic antigen; Terf, telomeric repeat binding factor; Tert, telomerase reverse transcriptase; Utf1, undifferentiated embryonic cell transcription factor. GTCM-2, TG343 and TRA are antibodies that detect epitopes on specific proteoglycans or associated proteins.

References cited in Table 2

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