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Expert Reviews in Molecular Medicine: http://www.expertreviews.org/
Accession information: Vol. 7; Issue 28; 9 December 2005 Abstract
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HLA class II alleles associated with rheumatic fever and rheumatic heart disease

Luiza Guilherme, Kellen Faé, Sandra E. Oshiro and Jorge Kalil

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Table 1. HLA class II alleles associated with rheumatic fever and rheumatic heart disease
HLA class II Countrya Refs
DR7 Brazil 13, 14, 15
Turkey 16
Egyptb 17
Latviab 18
DR4 USA 19, 20
Saudi Arabia 21
India 22
Other DR1 South Africa, Martinique 23, 24
DR2 USA, Mexico 19, 25
DR3 Turkey, India 16, 26
DR5 (11)c Turkey 27
DR6 (13)c South Africa, Egypt 17, 23
DR9 USA 19
DQA1*0104 Japan 28
DQB1*05031    

a Country of population in which association shown.
b In Egyptian and Latvian RHD patients, some DQ alleles in association with DR7 seem to be related to the development of multiple valvular lesions (Refs 17, 18).
c Alleles of DR5 and DR6.


References cited in Table 1

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14 Weidebach, W. et al. (1994) HLA class II antigens in rheumatic fever. Analysis of the DR locus by restriction fragment-length polymorphism and oligotyping. Hum Immunol 40, 253-258, PubMed

15 Visentainer, J.E. et al. (2000) Association of HLA-DR7 with rheumatic fever in the Brazilian population. J Rheumatol 27, 1518-1520, PubMed

16 Ozkan, M. et al. (1993) HLA antigens in Turkish race with rheumatic heart disease [see comment]. Circulation 87, 1974-1978, PubMed

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22 Bhat, M.S. et al. (1997) HLA antigen pattern of Kashmiri patients with rheumatic heart disease. Indian J Med Res 105, 271-274, PubMed

23 Maharaj, B. et al. (1987) HLA-A, B, DR, and DQ antigens in black patients with severe chronic rheumatic heart disease. Circulation 76, 259-261, PubMed

24 Monplaisir, N., Valette, I. and Bach, J.F. (1986) HLA antigens in 88 cases of rheumatic fever observed in Martinique. Tissue Antigens 28, 209-213, PubMed

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26 Jhinghan, B. et al. (1986) HLA, blood groups and secretor status in patients with established rheumatic fever and rheumatic heart disease. Tissue Antigens 27, 172-178, PubMed

27 Olmez, U. et al. (1993) Association of HLA class I and class II antigens with rheumatic fever in a Turkish population. Scand J Rheumatol 22, 49-52, PubMed

28 Koyanagi, T. et al. (1996) DNA typing of HLA class II genes in Japanese patients with rheumatic heart disease. J Mol Cell Cardiol 28, 1349-1353, PubMed

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