Expert Reviews in Molecular Medicine: http://www.expertreviews.org/
Accession information: Vol. 8; Issue 2; 17 January 2006 Abstract

Optical projection tomography showing Pkd1 expression in the mouse embryo

Bradley K. Yoder, Sharon Mulroy, Hannah Eustace, Catherine Boucher and Richard Sandford

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Movie 1. Optical projection tomography showing Pkd1 expression in the mouse embryo. A heterozygous Pkd1^del17-22bgeo E12.5 mouse embryo was stained with X-gal to demonstrate the expression of Pkd1 using a ‘knocked-in’ b-galactosidase reporter gene and imaged using optical projection tomography as described in Figure 4. Individual optical images of the whole mouse embryo were assembled to reconstruct the entire embryo. Stills from the movie are shown in Figure 4. Abbreviation: Pkd1, mouse polycystic kidney disease 1 gene.

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